Linalool: Therapeutic Indication And Their Multifaceted Biomedical Applications

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Drug Res (Stuttg). 2024 Jul;74(6):255-268. doi: 10.1055/a-2321-9571. Epub 2024 Jul 5.

ABSTRACT

This comprehensive review endeavors to illuminate the nuanced facets of linalool, a prominent monoterpene found abundantly in essential oils, constituting a massive portion of their composition. The biomedical relevance of linalool is a key focus, highlighting its therapeutic attributes observed through anti-nociceptive effects, anxiolytic properties, and behavioral modulation in individuals affected by dementia. These findings underscore the compound’s potential application in biomedical applications. This review further explores contemporary formulations, delineating the adaptability of linalool in nano-emulsions, microemulsions, bio-capsules, and various topical formulations, including topical gels and lotions. This review covers published and granted patents between 2018-2024 and sheds light on the evolving landscape of linalool applications, revealing advancements in dermatological, anti-inflammatory, and antimicrobial domains.

PMID:38968949 | DOI:10.1055/a-2321-9571