Vacuum fractional distillation of Cunila galioides Benth. essential oil: chemical composition and biological activities of raw oil and its fractions


Nat Prod Res. 2024 Jun 3:1-11. doi: 10.1080/14786419.2024.2360149. Online ahead of print.


This work aimed to rectify Cunila galioides essential oil and evaluate the raw oil and the fractions’ antifungal, allelopathic, and antioxidant activities. The results showed that the raw essential oil and the bottom fraction were primarily composed of linalyl propionate (42.9 wt.% and 60.2 wt.%). The top fraction was composed mainly of limonene (45.7 wt.%). The antioxidant activity changed with the radical and the fraction. The bottom had a weaker antifungal effect than the raw oil and the top. Nevertheless, the essential oil and the fractions had a similar antifungal activity at 0.50 % v/v and higher. Similar behavior was observed for the allelopathic tests. No difference occurred between the raw oil and the fractions, with reduced germination percentages and speed at 0.25 % v/v and complete inhibition at 0.50 % v/v. The oil can be rectified, and the fractions may be used without harming their biological activity.

PMID:38829275 | DOI:10.1080/14786419.2024.2360149