Three new pterosins from Pteris semipinnata

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Nat Prod Res. 2024 May;38(9):1591-1598. doi: 10.1080/14786419.2022.2162895. Epub 2023 Jan 12.

ABSTRACT

Three new pterosins, named as semipterosin A (1), B (2) and C (3), together with 11 known pterosins (4-14), were isolated from the aerial parts of Pteris semipinnata. Their structures were elucidated by HRESI-MS, NMR spectral data, CD and literature comparisons. Three new pterosins were assessed for their anti-inflammatory activity. Compounds 1-3 inhibited the NF-kB induction by 40.7%, 61.9% and 34.0%, respectively. This is the first report of the isolation of compounds 6-14 from this plant.

PMID:38573587 | DOI:10.1080/14786419.2022.2162895